Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01253Lenalidomide0.047477%
BADD_D01254Lenvatinib--
BADD_D01257Letrozole0.003691%
BADD_D01261Leuprolide monoacetate--
BADD_D01270Levocabastine hydrochloride--
BADD_D01275Levofloxacin0.000433%
BADD_D01280Levomilnacipran hydrochloride--
BADD_D01281Levonorgestrel--
BADD_D01285Levothyroxine0.000138%
BADD_D01290Lifitegrast0.037645%
BADD_D01307Lodoxamide--
BADD_D01308Lodoxamide tromethamine--
BADD_D01319Lorcaserin hydrochloride--
BADD_D01320Lorcaserin hydrochloride hemihydrate--
BADD_D01324Loteprednol etabonate0.001097%
BADD_D01326Loxapine--
BADD_D01336Macitentan--
BADD_D01397Mesalamine--
BADD_D01401Metformin--
BADD_D01418Methotrexate0.004480%
BADD_D01431Methylphenidate--
BADD_D01445Metoprolol0.000078%
BADD_D01446Metoprolol succinate--
BADD_D01447Metoprolol tartrate--
BADD_D01475Mirabegron0.000828%
BADD_D01476Mirtazapine0.000365%
BADD_D01491Mometasone furoate0.001243%
BADD_D01501Moxifloxacin0.000578%
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01507Mycophenolate mofetil0.001962%
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